March Madness — 2/27/26

2026 Men’s March Madness Bracket Lookout: Duke, UConn, Michigan, Arizona Lead the Championship Chase

By 
drew
WagerWire Contributor

March Madness is approaching, and the projected 2026 NCAA Men’s Tournament bracket is stacked with blue bloods, rising contenders, and dangerous bubble teams. Four programs, Duke, UConn, Michigan, and Arizona, sit on the No. 1 seed line, but history tells us the path to a national title is never easy.

Here’s a visual region-by-region breakdown and outlook at the projected field.

EAST REGION – Duke Controls the East

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The Duke Blue Devils headline the East as the No. 1 overall seed, with elite depth and championship expectations.

Key Matchups

1 Duke vs 16 App State

8 Iowa vs 9 Georgia
→ Classic toss-up game

5 St. John’s vs 12 Liberty
→ Liberty is a dangerous mid-major

4 Alabama vs 13 North Dakota State

6 Louisville vs 11 Missouri / Santa Clara

3 Kansas vs 14 Austin Peay

7 Utah State vs 10 UCF

2 Purdue vs 15 Utah Tech

East Favorite: Duke

Sleeper: Kansas

Upset Alert: Liberty over St. John’s

SOUTH REGION – UConn and Houston on Collision Course

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The defending powerhouse UConn Huskies lead the South, but Houston could be their biggest threat.

Key Matchups

1 UConn vs 16 UMBC / Howard

8 Kentucky vs 9 Clemson

5 Arkansas vs 12 Yale

4 Texas Tech vs 13 UNC Wilmington

6 Saint Louis vs 11 Miami (OH)

3 Nebraska vs 14 Navy

7 Wisconsin vs 10 Texas

2 Houston vs 15 Portland State

South Favorite: UConn

Final Four Threat: Houston

Sleeper: Texas

MIDWEST REGION – Michigan Faces Dangerous Field

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The Michigan Wolverines hold the top spot, but Iowa State and North Carolina could make deep runs.

Key Matchups

1 Michigan vs 16 SEMO / Bethune-Cookman

8 SMU vs 9 Texas A&M

5 Vanderbilt vs 12 Belmont

4 Virginia vs 13 Stephen F Austin

6 North Carolina vs 11 TCU / New Mexico

3 Florida vs 14 ETSU

7 Villanova vs 10 UCLA

2 Iowa State vs 15 Wright State

Midwest Favorite: Michigan

Sleeper: North Carolina

Dangerous Team: Iowa State

WEST REGION – Arizona Headlines Loaded West

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The Arizona Wildcats lead the West, but this may be the toughest region overall.

Key Matchups

1 Arizona vs 16 Long Island

8 Miami vs 9 Saint Mary’s

5 Tennessee vs 12 South Florida

4 Michigan State vs 13 High Point

6 BYU vs 11 Indiana

3 Gonzaga vs 14 UC Irvine

7 NC State vs 10 Auburn

2 Illinois vs 15 Merrimack

West Favorite: Arizona

Sleeper: Indiana

Upset Watch: Auburn over NC State

Bubble Watch: Teams Fighting for Survival

Last Four Byes (Barely Safe)

  • Texas
  • UCLA
  • Auburn
  • Indiana

Last Four In (Must Win First Four)

  • Missouri
  • Santa Clara
  • TCU
  • New Mexico

First Four Out (Just Missed)

  • Ohio State
  • USC
  • California
  • San Diego State

Conference Power Rankings

Most Teams in Field

  • SEC – 11 teams
  • Big Ten – 9 teams
  • ACC – 8 teams
  • Big 12 – 8 teams

The SEC is dominating the bracket with depth and elite contenders.

Final Four Prediction

Based on the bracket projection:

  • Duke
  • UConn
  • Michigan
  • Arizona

National Championship Prediction

Duke vs UConn

Winner: Duke

The Blue Devils have the depth, talent, and momentum to cut down the nets.

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